Bone Marrow Report Template

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Sex F M

No flow cytometry

With flow cytometry

ALC ×

Comment

A definite etiology for the patient's *** is difficult to ascertain by morphology and *** flow cytometry of the current specimen. Overt leukemia or lymphoma is not identified. The overall findings are nonspecific, and the differential diagnosis includes autoimmune disorders, drug or toxin exposure, hormones or growth factors, vitamin or essential element deficiencies, and viral infections, as well as a subtle myeloid neoplasm. A subset of monocytes expresses dim CD56, an atypical feature which can be seen in myeloid neoplasms, but nonspecific and frequently seen as a reactive process, e.g. in association with viral infections. If unexpectedly persistent or increasing, consideration may be given to further studies, if clinically indicated. Correlation with concurrent genetic studies is suggested. Correlation with concurrent genetic and minimal residual disease studies is suggested. Correlation with genetic studies is required for classification. In the absence of a defining genetic abnormality, the current findings meet criteria for ***. The findings may indicate a low-grade myelodysplastic neoplasm (MDS); however, correlation with clinical and molecular genetic findings is required to exclude non-clonal, secondary, or transient dysplasia (e.g., drug and toxin exposure, viral infections, immunologic disorders, nutritional deficiencies (vitamin B12 or copper)). Non-clonal causes of dysplasia must be excluded before the diagnosis of MDS is established.

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Flow Cytometry

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Flow comment

Atypical cells immunophenotype